• Those dealing with systemic inflammation and looking for targeted modulation support
• Individuals with inflammatory skin conditions wanting a complementary internal approach
• People with gut lining concerns or known intestinal permeability issues
• Those exploring inflammation-modulating strategies alongside dietary and lifestyle change

KPV is a Lysine-Proline-Valine tripeptide that interacts with inflammatory signalling cells in the body, including mast cells and other immune-adjacent tissue. It may support gut barrier function and modulate the intestinal immune response, while also offering skin-supportive properties from the inside. KPV is often used as a cornerstone of an anti-inflammatory protocol, paired with gut-focused products and dietary changes.

KPV is taken daily alongside a whole-food, low-processed diet. It works well in combination with gut-focused support products and is often used for 4–8 week protocols. Reducing dietary inflammatory drivers — processed foods, refined sugar, and alcohol — gives KPV the best environment to work in.

• Gut Feeling — For comprehensive gut barrier and microbiome support alongside KPV's anti-inflammatory action.
• BPC-157 PURE Delayed Release — To complement gut lining integrity with systemic tissue repair support.
• Thymogen Alpha-1 — For immune modulation support alongside inflammation management.

If you have a diagnosed inflammatory bowel disease, autoimmune condition, or skin condition requiring medical management, please consult your healthcare provider before beginning KPV. It is intended as a complementary tool within a broader wellness approach, not a replacement for prescribed treatment.

Is KPV the same as alpha-MSH?

KPV is the C-terminal tripeptide fragment of alpha-MSH (alpha-melanocyte stimulating hormone) and shares some of its anti-inflammatory properties. It does not carry the full hormonal profile of alpha-MSH, which makes it a more targeted and safer option for supplementation purposes.

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What is the KPV Ultra Oral Spray?

The KPV Ultra Oral Spray provides an alternative sublingual delivery format for faster mucosal absorption. If you are exploring which format is most appropriate for your goals, we recommend booking a Personalized Wellness Consultation.

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Can KPV be used during an active flare?

KPV is generally considered a gentle, modulatory approach rather than an acute intervention. For active flares of inflammatory conditions, we recommend consulting your healthcare provider first to ensure supplementation is appropriate alongside any prescribed treatment.